Agenda

9:00 - 11:00 AM 

I2I Pitch Competition at the Feinstein’s Hotel Nikko - (Reservation Required) 

Advocates: 
Susie Brain, UCSF Breast Science Advocacy Core
Heather Salazar, Pink Ribbon Good

11:00 - 11: 40 AM

Re-Imagine Toxicity and Reducing Drug Manufacturing costs: A call to action to VCs

• Laura Esserman, MD, MBA, University of California, San Francisco Breast Care Center 
• James Fraser, PhD, University of California, San Francisco, Department of Bioengineering and Therapeutic Sciences 
• Dan Hartman, MD, The Gates Foundation 
• Andrea Olariu, Medicines 360 

Advocate: 
Vivian Lee, UCSF Breast Science Advocacy Core

11:40 - 11:50 AM

I2I Closing Remarks (Results Announced Saturday) 

12:00 - 1:30 PM

Luncheon (Reservation Required)  

2:00 - 2:05 PM

Conference Opening - Welcome: Where we have been, what we know, what we don't, and opportunities for intervention: Accelerating learning in prevention, our approach to hormonal interventions 

2:05 - 2:45 PM

Keynote: A Big Vision for Primary and Secondary Prevention

Moderator: Laura Esserman, MD, MBA 

Moving Imaging Forward as an Early Endpoint
Fiona Gilbert, MD, University of Cambridge 

Designing New Targeted, Less Toxic Agents 
James Fraser, PhD, University of California, San Francisco

What will it take to energize pharmaceuticals to get behind affordable prevention agents?  
Dan Hartman, MD, The Gates Foundation 

2:45 - 4:00 PM

Session 1: Personalized Screening and Other Risk Assessment Trials (WISDOM, MyPeBS)

Co-Chairs: 
Laura Esserman, MD, MBA, University of California, San Francisco 
Suzette Delaloge, MD, MSc, Gustave Roussy

Advocate: 
Dolores Moorehead, Women's Cancer Resource Center

4:05 - 5:20 PM

Session 2: Overcoming Resistance from the Ground Up: What are the Drivers and How Can They Inform Our Prevention Approach?

Co-Chairs: 

 Laura van ‘t Veer, PhD, University of California, San Francisco 

Lajos Pusztai, MD, DPhil, Yale University 

Advocate: 

Valerie Fraser, SWOG Cancer Research Network Patient Advocates Committee

5:25 - 5:55 PM

Ideas to Implementation Awards

6:00 - 7:30 

Poster Session 1 -- Appetizers

8:00 - 9:15 AM

Session 3: Early Imaging Endpoints to Accelerate the Learning Cycle (Rise Assessment and Response) 

Co-Chairs: 
Nola Hylton, PhD, University of California, San Francisco 
Elissa Price, MD, University of California, San Francisco 

Advocate: 
Carolyn Clark Beetle, UCSF Breast Science Advocacy Core

9:20 - 10:45 AM

Session 4: Risk Biomarkers as Indicators of Response in Prevention and Treatment Trials: One Size Doesn't Fit All

Co-Chairs: 
Carol Fabian, MD, The University of Kansas Medical Center 
Jo Chien, MD, University of California, San Francisco 

Advocate: 
Amy Delson, UCSF Breast Science Advocacy Core

Invited Speakers:  
Mammo AI 
Graham Colditz, MD, DrPH, Washington University 

10:50 - 12:05 AM

Session 5: Impact from Treatment to Prevention: Translational Prevention Trials

Co-Chairs:
Seema Khan, MD, Northwestern University 
Andrea De Censi, MD, Champalimaud Foundation 

Advocate: 
Jan Tomlinson, UCSF Breast Science Advocacy Core

12:05 - 12:10 PM

12:10 - 12:25 PM

I2I 2024 Winner Talk: “A potential for both treatment-resistant tumors and prevention? Control of the estrogenic stimulation of the breast via the ubiquitous androgen receptor pathway” 

Stephen Birrell, MD, PhD, FRACS, Dame Roma Mitchell Cancer Research Laboratories 

Wayne Tilley, PhD, Dame Roma Mitchell Cancer Research Laboratories 

12:25 - 1:40 PM

Poster Session 2 (Lunch Included)

1:45 - 3:00 PM

Session 6: The Landscape of Reproductive Healthcare in the United States

Co-Chairs: 
Lynn Yee, MD, MPH, Northwestern University 
Madeline Perry, MD, University of Pennsylvania 
Dan Grossman, MD, University of California, San Francisco 

Advocate: 
Jessica Pinckney Gil, Access Reproductive Justice 

Invited Speakers

3:05 - 4:35 PM

Session 7:  Rethinking Contraceptives: Current Risk for Breast Cancer and Potential Future Combinations. Can Treatment of Benign Uterine Conditions Provide a Path for Breast Cancer Prevention? 

Co-Chairs: 

Diana Blithe, PhD, The National Institutes of Health  

Carolyn Westhoff, MD, MSc, Columbia University 

Sandra M Laveaux, MD, MPH, University of Chicago 

4:50 - 5:05 PM

I2I 2024 Winner Talk: "Novel breast cancer prevention strategies utilizing epigenetic markers and antiprogestins"

Martin Widschwendter, MD, University College London

5:10 - 6:25 PM

Session 8: Tissue and imaging combinations that elucidate a new way to think about treatment and prevention: Postpartum Breast Cancer

Co-Chairs: 
Virginia Borges, MD, University of Colorado 
Matteo Lambertini, MD, PhD, University of Genova 

Advocate: 
Lynda Weatherby, Our MBC Life Podcast

Invited Speakers 
Cristina Saura, MD, PhD, Vall d’Hebron University Hospital

6:30 - 8:30 PM

Conference Dinner that Promotes Conversation & Discussion: A Meeting of the Minds

7:30 - 8:45 AM

Poster Session 3

8:45 - 10:00 AM

Session 9: Innovative Strategies for Community Engaged Research to Accelerate Progress in Women's Health

Co-Chairs: 
Olufunmilayo Olopade, MD, University of Chicago 
Ricki Fairley, TOUCH, The Black Breast Cancer Alliance 
Damé Idossa, MD, Mayo Clinic 

Advocate: 
Ricki Fairley, TOUCH, The Black Breast Cancer Alliance 

10:05 - 11:20 AM

Session 10: Environment, the Exposome, and Inflammation as a Mediator of Breast Cancer Risk

Co-Chairs: 
Kimberly Badal, PhD, University of California, San Francisco 
Peggy Reynolds, PhD, MPH, MA, University of California, San Francisco 

Advocate: 
Nancy Buermeyer, Breast Cancer Prevention Partners
 

11:25 - 12:40 PM

Session 11: Lifestyle-based Prevention Strategies

Co-Chairs: 

Jennifer Ligibel, MD, Harvard University 

Katrine Whiteson, PhD, University of California, Irvine 

Advocate:

Elizabeth Watson, UCSF Breast Health Clinic Volunteer

12:45 - 1:00 PM

I2I 2024 Winner Talk: “Innovative Fitness Solutions for Health Equity in Cancer Care”

Jennifer Johnson, JennJ Health

1:00 - 2:15 PM 

Lunch

2:15 - 3:30 PM

Session 12: Treating Obesity / Obesity in the Context of the Larger Hormonal Picture 

Co-Chairs: 
Stephen Hursting, PhD, University of North Carolina at Chapel Hill 
Neil Iyengar, MD, Emory University 

Advocate: 
Julia Laursen, For the Four 

Invited Speakers:  
Microbiome in Obesity 
Katherine Cook, PhD, Wake Forest University 

3:35 - 3:50 PM

I2I 2024 Winner Talk: “Biomarker of tirzepatide effectiveness for cancer”

Erin Giles, PhD, University of Michigan

4:05 - 5:20 PM

Session 13:  Menopausal Hormone Therapy and Alternatives for High-risk Women Without Cancer

Co-Chairs: 

Lisa Larkin, MD, FACP, MSCP, Ms. Medicine 

Erin Duralde, MD, MPH, MSCP, One Medical 

Advocate:

Tracey Heather, Patient Engagement Lead, Quantum Leap Healthcare Collaborative 

5:20 - 5:30 PM

Special Talk: IVF and Long-Term Outcomes

Speaker:
 Mitchell Rosen, MD, University of California, San Francisco 

5:30 - 6:50 PM

Session 14: Menopausal Hormone Therapy and Alternatives for Women with Cancer

Co-Chairs: 

Hope Rugo, MD, City of Hope 

Abigail Liberty, MD, MSPH, Oregon Health & Science University 

6:50 - 6:55 PM

Closing Remarks