Conference Day 1 - Thursday, February 19th, 2026
9:00 - 11:00 AM
11:00 - 11: 40 AM
11:40 - 11:50 AM
12:00 - 1:30 PM
1:45 - 2:00 PM
2:00 - 2:20 PM
I2I Pitch Competition at the Feinstein’s Hotel Nikko - (Reservation Required)
Re-Imagine Toxicity and Reducing Drug Manufacturing costs: A call to action to VCs
I2I Closing Remarks (Results Announced Saturday)
Luncheon (Reservation Required)
Conference Opening - Welcome: Where we have been, what we know, what we don't, and opportunities for intervention: Accelerating learning in prevention, our approach to hormonal interventions
Keynote: How do we do something revolutionary that has never been done before?
2:20 - 3:10 PM
Panel Discussion: A big vision for primary and secondary prevention
Trials that Transform Our Approach to Screening and Prevention
3:20 - 4:50 PM
4:50 - 5:50 PM
Session 1: Rethinking our screening approach: An overview of Personalized Screening and other Risk Assessment Trials (WISDOM, MyPeBS)
Session 2: Impact from treatment to prevention: Translational Prevention Trials
6:00 - 7:30 PM
Poster Session 1 & Appetizers
Conference Day 2 - Friday, February 20th, 2026
Scalable Early Endpoints to Accelerate the Learning Cycle
8:00 - 9:00 AM
Session 3: Overcoming resistance from the ground up: What are the drivers, and how can they inform our prevention approach?
9:00 - 9:15 AM
I2I 2024 Winner Talk: “A potential for both treatment-resistant tumors and prevention? Control of the estrogenic stimulation of the breast via the ubiquitous androgen receptor pathway”
Stephen Birrell, MD, PhD, FRACS, Dame Roma Mitchell Cancer Research Laboratories
Wayne Tilley, PhD, Dame Roma Mitchell Cancer Research Laboratories
9:15 - 10:30 AM
11:00 - 12:00 PM
Session 4: Early Imaging Endpoints to Accelerate the Learning Cycle (Risk Assessment and Response)
Session 5: Early Endpoints (Tissue/Blood/Saliva/path AI-based biomarkers) to Accelerate the Learning Cycle: biomarker candidates for both treatment response & prevention (benign disease, DCIS & EOP)
12:00 - 1:15 PM
1:15 - 2:30 PM
2:30 - 3:30 PM
Poster Session 2 (Lunch Included)
Session 6: Dobbs Decision & the series of new state laws: Impact on Women
Session 7: DEI as fundamental to personalized medicine: best techniques to trial promote enrollment across all groups
3:45 - 5:00 PM
5:00 - 7:00 PM
Session 8: Tissue and imaging combinations that elucidate a new way to think about treatment and prevention: Postpartum Breast Cancer
Conference Dinner that promotes conversation & discussion: A meeting of the minds
Conference Day 3 - Saturday, February 21st, 2026
8:00 - 9:00 AM
Poster Session 3
Modifiable Risk Factors
9:00 - 10:30 AM
Session 9: Environment, the Exposome & Inflammation as a Mediator of Breast Cancer Risk
10:30 - 11:30 AM
Session 10: How do we reduce the risk of developing obesity or metabolic syndrome?
11:30 - 12:30 PM
I2I 2024 Winner Talk: “Innovative Fitness Solutions for Health Equity in Cancer Care”
Jennifer Johnson, JennJHealth
12:30 - 1:00 PM
Lunch
1:00 - 2:00 PM
2:00 - 2:15 PM
Session 11: Treating Obesity / Obesity in the Context of the Larger Hormonal Picture
I2I 2024 Winner Talk: “Biomarker of tirzepatide effectiveness for cancer”
Erin Giles, PhD, University of Michigan
2:15 - 3:15 PM
Session 12: Rethinking Contraceptives: current risk for breast cancer and potential future combinations
3:15 - 3:30 PM
I2I 2024 Winner Talk: "Novel breast cancer prevention strategies utilizing epigenetic markers and antiprogestins"
Martin Widschwendter, MD, University College London
3:40 - 4:40 PM
4:40 - 5:40 PM
5:40 - 6:40 PM
Session 13: Postmenopausal hormone replacement therapy & alternatives in high-risk women without cancer: Balancing breast, brain, libido, hot flashes
Session 14: Hormonal therapy & alternatives in women with cancer: Balancing breast, brain, libido, hot flashes
Session 15: Can treatment of benign uterine conditions provide a path for breast cancer prevention?
6:40 - 7:00 PM
I2I Awards Announced & Closing Remarks